MK-677 (also known as Ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, Ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.
Therefore, we can expect that ibutamoren may also affect these functions. It increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.
But What actually is MK-677? What effects can you expect from its use? Does it have any side effects? What should you consider before buying? We answer these and other questions in the following article.
Ibutamoren, also known as MK-677 and Nutrobal, is a substance developed by Merck & Co. in the early 21st century. Often wrongly categorized as SARMs (Selective Modulators of Androgen Receptors) or referred to as growth hormone in pills/liquid. Ibutamoren MK-677 capsule is a substance that stimulates the secretion of growth hormone and insulin-like growth factor IGF-1.
This means that Ibutamoren does not directly affect the levels of these hormones, but only indirectly signals the body to produce more of them. It binds to the GHSR receptors and thus also affects all related functions – appetite, mood, memory, biological rhythm and cognitive ability. Ibutamoren is currently being studied for its ability to prevent muscle wasting and obesity-related diseases, increase bone density, and serve as a remedy for hormone deficiencies. Recent clinical trial results confirm reviews of people who have used MK-677 to date and prove that the high hopes placed in this substance were not unfounded.
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